Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Thickening or hollowing of the skin where you injected the medicine. Skin rash, itching, redness, or swelling or Low potassium-leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.Ĭommon side effects of insulin aspart may include: Heart problems-swelling, rapid weight gain, feeling short of breath or Insulin aspart may cause serious side effects. Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.